What are the characteristics of effervescent tablets? What are the requirements for packaging?

Effervescent tablet is a relatively new type of pharmaceutical dosage form. Different from ordinary tablet, effervescent tablet uses organic acid and basic carbonate reaction as effervescent disintegrant. When placed in water, an effervescent reaction occurs immediately and a large amount of carbon dioxide is generated. gas. What are the characteristics of such a special dosage form and what are the requirements for packaging?

At present, the effervescent tablets on the market are divided into oral and external categories. The external type is generally medicinal and is mainly used to treat gynecological inflammation. The oral type is mainly health-care effervescent tablets, such as vitamin C effervescent tablets and multi-dimensional effervescent tablets. , calcium effervescent tablets and iron effervescent tablets, etc. Oral effervescent tablets have the advantages of being convenient to take, easy to carry, and quick to take effect. They are suitable for the elderly, children and patients who have difficulty swallowing drugs, but they should not be left for too long after soaking to avoid affecting the efficacy of the drug.

Combined with the characteristics of the effervescent tablet, we can summarize its functional requirements for the effervescent tube: easy to carry, sealed and moisture-proof. First of all, from the perspective of portability, the capacity of the effervescent tube should not be too large. The commonly used capacity is 99mm/133mm/144mm, and the number of tablets placed should not exceed 20. Pharmaceutical companies can choose the corresponding capacity according to the thickness of the tablet.

The second is sealing and moisture-proof. This factor is mainly controlled by the packaging material and desiccant. The material is generally made of polypropylene material with good waterproof performance, which can meet the requirements of moisture-proof. In order to ensure the dryness of the environment in the bottle, pharmaceutical companies generally require a desiccant to be placed in the effervescent tablet bottle. The desiccant can absorb the moisture in the air and ensure the dryness of the tablet.