How to detect the air tightness of medical plastic bottles


Medicinal plastic bottles play a role in the protection […]

Medicinal plastic bottles play a role in the protection of medicines. Nowadays, more and more types of medicines are used in different packaging. Different materials may react with medicines. So how to choose medicinal packaging?
If we need packaging bottles with high transparency, we choose this kind of polyester plastic bottle, and if it is some drugs that do not need to be exposed to light, we choose brown plastic bottles. There are many kinds of materials to choose from, and no matter what material you choose, the medicinal plastic bottle has a very important influence on the goods to be packaged. The size and cap of the plastic bottle have special requirements, and the cap should be made of pp material. Generally, plastic bottles of tablet materials are usually made of high-density polyethylene. In general, polypropylene or polyester bottles are used as the main material for drugs in liquid dosage forms. The infiltration and secretion of water vapor and the tightness of the bottle are important indicators of plastic bottles. Whether they are qualified or not is related to the quality and safety of the medicines.

The air-tightness of medical plastic bottles is important for preventing moisture and deterioration of medicines during the validity period. It is also an important medium to prevent the influence of light, heat, oxygen, etc. on medicines. Therefore, as a pharmaceutical plastic bottle manufacturer, we attach great importance to its air tightness testing.
What is the air tightness of medical plastic bottles? Simply speaking, it is tested according to relevant national standards. For example, the reliability of the sealing of plastic capsule bottles is tested by taking a certain number of plastic capsule bottles, filling each bottle with an appropriate amount of glass balls, and tightening the cap. Then put it into a container with an air extraction device, immerse it in water, and vacuum to a vacuum of 27kpa and maintain it for 2 minutes. There should be no water or bubbles in the bottle. Of course, to ensure the air-tightness of the plastic bottle capsule through the index, some other economic indicators, such as resistance, moisture resistance and oxygen resistance, and control are needed to ensure the quality of the shelf life product.
There are also machines on the market that have introduced a sealing tester. Using the principle chamber vacuum of a vacuum cleaner, the pressure difference between the internal and external pressures of the medicinal plastic bottle submerged in water is produced, and the gas escape inside the sample is observed to determine the sealing performance. : Or through the vacuum chamber, make the sample production internal and external pressure difference, observe the inflation of the sample and the recovery of the sample shape after the vacuum is released, in order to determine the sealing performance.